We will discuss our findings in the functional and physiological brain changes in schizophrenia patients measured by advanced MRI methods developed by us. These include functional connectivity, neurovascular and metabolic changes in the human brain.

Dr. Hua’s research has centered on the development and application of novel MRI technologies for in vivo functional and physiological imaging in the brain. These include the development of human and animal MRI methods to measure functional brain activities, cerebral perfusion and oxygen metabolism at high (3 Tesla) and ultra-high (7 Tesla and above) magnetic fields. He is particularly interested in novel MRI approaches to image small blood and lymphatic vessels in the brain. Collaborating with clinical investigators, these techniques have been applied to detect functional, vascular and metabolic abnormalities in the brain in neurodegenerative diseases.